QLTI-05. HBA1C AND INSULIN COVERAGE FOR NEWLY DIAGNOSED HGG PATIENTS IN THE HOSPITAL

Abstract Corticosteroids are used in the management of patients with high-grade gliomas (HGG). lead to elevated serum glucose levels, necessitating sliding-scale insulin. A hemoglobin A1c (HbA1c) reflects historical levels but it’s unclear if it predicts corticosteroid-induced hyperglycemia. We retrospectively reviewed all newly diagnosed HGG who were admitted between Jan 2019 July 2021 had an HbA1c performed at time their diagnosis. is classified into: normal (< 5.6%), (5.7 – 6.4%) and diagnostic (> 6.5%). identified 86 whom 29 16 HbA1c, respectively. These more likely require sliding scale insulin least twice during hospitalization, 64% vs 13% those a HbA1c. Only 28% history diabetes. There was no correlation likelihood initiating post-operative therapy, surgical complications, or BMI results. When reviewing age, 39 less than 65, which 34% Of older 65% Our analysis suggests there predictive value need for while receiving corticosteroids population, especially population. recommend screening new diagnosis, regardless they have also monitoring frequently If diagnostic, should monitored available patient > 65 years be considered higher risk having hyperglycemia reviewed. Further being conducted will later date.